• Paddle and baskets are the different type of the apparatus used in dissolution to find the drug release.
• Generally, baskets are used for capsule or ur tablet flotting in media. paddle can be used for all.
• Some times paddle is also used in the capsule and flotting tablets by using sinker to achieve appropriate result.

Paddle Dissolution Method:

• In this method, the rotating shaft is fixed to a blade attached vertically at the end.
• This blade is meant to act as a stirrer to mix the drug being tested with the liquid inside the holding vessel.
• Typically, the drug is placed inside the holding vessel and once it settles at the bottom, the rotating shaft is switched on to begin mixing.
• The drug being tested is also frequently attached to a sinker to prevent the drug from attaching itself to the vessel walls and also to ensure the drug being tested remains positioned beneath the rotating shaft.
• This sinker is made from a non-reactive element to prevent it from reacting with the drug sample it holds.

Basket Dissolution Method

• In the basket dissolution method, a different apparatus is placed at the end of the rotating shaft. This apparatus is called a basket.
• It is cylindrical in shape and is constructed from non-reactive mesh to prevent any unwanted chemical reactions that may alter the final result.
• The pores in the mesh allow the dissolving drug to move from the basket into the holding vessel, creating a uniform solution.
• The drug being tested is first placed inside the basket that is firmly attached to the end of the rotating shaft.
• Once the drug is securely in place, the motor is switched on and the shaft begins rotating the basket inside the vessel.
• The sticky tablets containing HPMC or similar compounds as a binder are tested using a basket because tablet swells in water and may stick to the walls of the dissolution vessel.